Published on: August 19, 2024
Hey guys, make a justifiable response for the following.
As the worldwide response to the novel coronavirus (COVID-19) continues, nurses are working to assist the sick, quell community fears and address concerns. Nurses, the largest sector of healthcare workers in every country, play a pivotal role in preparation for a possible pandemic. The nurses' role in a pandemic begins even before a disease has an opportunity to cause widespread devastation, the World Health Organization (WHO), the American Nurses Association (ANA) and other healthcare organizations said. In a 2018 policy brief, the ANA said nurse leaders are the key to preventing and containing widespread illnesses. They have the skills and education to develop coordinated global networking and properly identifying of infectious diseases. As frontline responders, nurse leaders are the first to recognize symptomatic patients and harmonize response efforts, the ANA said. ""The American Academy of Nursing asserts that nurses are prepared for the leadership roles in policy decisions of health systems and government agencies and can prepare for, identify, respond to and direct recovery efforts from global pandemics that require an informed, internationally coordinated response,"" the ANA said in ""Expanding nursing's role in responding to global pandemics."" In preparation for advanced roles, registered nurses (RNs) who earn a master's in nursing degree (MSN), including through online master's in nursing programs, can be prepared for the worst. In an MSN career, RNs have an opportunity to provide expert help and guidance through devastating illnesses, including COVID-19.
1. In a fact-filled manner, rationalize or falsity the following concerning the polypeptide second configuration.
The hydrophobic/hydrophilic quality of amino elements is vital to secondary configuration.
2.Basically, given a double portion of polypeptides have a mutual scope of series
recognition during chain configuration, a similar execution has low chances of being
shared. Is the inference true or false? Elucidate.
3.State three facts about secondary polypeptide arrangement.
4.identify the least complex amino elements series and state its components.
5.Using data from genomes, determine the mechanism that interlinks
the cell configuration incident in animals.
6.Basically, what initiates the convenience of polythene chromosomes? Describe the mechanism.
7.Fundamentally, an arrangement with hydrogen bonds between polypeptide chains set
side by side is?
8.Alternative sorts of facts for a relationship between two genes are also given that are
not dependent in sequence similarity. Falsify or justify the following.
phylogenetic outlines unveil the genes are not that regularly present in organisms
9.From bioinformatics concept, determine an integral implication of the two inferences
below.
Genes are transcribed from the same DNA strand and genes are closely connected on
the same chromosomes
10.What is the implication of the inference below basing on bioinformatics concepts?
Gene syntheses are pragmatic amid otherwise distinct genes."
Some comments in relation to Nursing Roles in a Pandemic
The Legal Profession and the Current Pandemic
Nurses being the largest profession in the field of healthcare are instrumental in combating and containing diseases such as COVID-19. The nurses also have the responsibility of early identification, reporting of the disease and coordination in the management and control of infection diseases according to WHO and ANA. Senior nurses with education and experience have influential roles in the global health policy and can steer the global coordinated response. They are the first line in the diagnosis of infectious diseases and are most likely to note signs of a sick person and put in measures to ensure adequate response is initiated.
When nursing professionals are aiming at assuming more in-depth leadership roles during such global health emergencies, they may seek for Master’s in Nursing (MSN). Clinical experience together with leadership skills enables these professionals to bring their best in implementing the strategies that will reduce the spread of diseases to the population.
Answers to Polypeptide and Bioinformatics Questions
Appearence of Hydrophobic / Hydrophilic property of Amino Acids in Secondry structure
It’s true that hydrophobic and hydrophilic characteristics of amino acids are tremendously important for secondary structures. Hydrophobic residues are often found in the protein’s interior, whereas hydrophilic ones are found externally. This distribution helps in the formation of alpha helices and beta sheets by maintaining the hydrogen bonding that are involved.
The concept of mutual scope in polypeptide chain configuration is as follows.
The statement is true. There can be differences in the interactions between side chains in two polypeptides, the bond between atoms or chains, or the environment (such as pH or temperature) which may result in gross differences in configuration even where the primary structures are similar. This process is very sensitive to these and many other factors.
The following are changes are attributes of Secondary Polypeptide Arrangement;
Among the secondary structures, alpha helices and beta sheets are abundantly found.
Secondary structure is stabilised predominantly by the hydrogen bonds of the backbone amides.
The nature of the amino acid determines whether a region of the polypeptide is going to be in the form of alpha helix, beta sheet or it is going to have random coiling.
Simplest Amino Acid Sequence
This product is referred to as glycine and due to the presence of only single hydrogen side chain, it is considered the simplest of all the amino acids. It brings conformational flexibility to polypeptide chains, and is often seen in turns or loops of a protein.
Signalling Process that Connects Cell Configuration Events in Animals through Genome Information
It is the modulation of genes by using transcription factors and enhancers. Cell signaling such as Wnt, Hedgehog, Notch and others are involved in the regulation of cellular processes during development and according to the genomic regulatory elements.
Initiation of Polytene Chromosomes
Polytene chromosomes are formed when there is a DNA replication without cell division to result in large chromosome masses which are visible. They are present in some organisms such as Drosophila and are important in gene expression analysis.
Organization with Hydrogen Bonds Side Chain to Side Chain
Beta-sheet has hydrogen bonds between one polypeptide chain and the other either parallel or antiparallel to each other.
Hierarchical or Analogous Interactions of Genes which are not Structurally Aligned
The statement is justifiable. This is because using phylogenetic analysis one may see that gene presence or absence in the examined organisms may or may not correspond to the level of sequence similarity, for instance in case gene loss, horizontal gene transfer or convergent evolution has taken place.
A Consequence of Genes Transcribed from the Same Strand or Which Are Neighboring
When genes are co-transcribed or are neighbours or in close physical proximity, it is likely that they are regulated and function together for example in the same pathway.
Promoting Both Scission and Synthesis While Otherwise Rather Discrete Genes
Such outcomes imply that those genes may be regulated in a similar method at certain circumstances, thus can provide an indication of coordinated regulation mechanisms for these genes even if they belong to different functional classes.
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