Published on: August 19, 2024
Antibiotics that are effective against Gram-negative bacteria include several key classes and specific drugs:
Beta-lactams: Included in this class are carbapenems such as the imipenem and meropenem as well as extended spectrum cephalosporins such as ceftriaxone and ceftazidime. These antibiotics are widely prescribed for severe GN infections often in the hospital environment.
Aminoglycosides: Some of them include gentamicin and amikacin which are normally used jointly with other antibiotics for severe infection.
Fluoroquinolones: Some of the antibiotics used in the treatment of the Gram-negative bacteria are the ciprofloxacin and levofloxacin which are used in the treatment of urinary tract and respiratory tract infections.
Polymyxins: Polymyxin E also known as colistin and polymyxin B are only employed for the treatment of MDR Gram-negative organisms especially P. aeruginosa and A. baumannii.
Monobactams: It is a monobactam antibiotic that is active against Gram-negative organisms and it can be used in patient who have penicillin allergy.
Tetracyclines: Here, doxycycline is occasionally prescribed for specific Gram-negative bacteria; however, it is also possible to experience resistance.
Of all the bacterial types, gram-negative bacteria are difficult to manage with anti-biotics because they can easily develop a resistance. This features E. coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter species (World Health Organization (WHO)) (CDC) (Drugs. com).
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